<b>Effects (most volatile)
</b><ul>
<ul><li>Marked drop in gamma band activity (25 – 50Hz)</li><li>Increase in theta/delta frequencies  (Theta comes from inhibition of normal thalamic pacemaker cells, Delta results from extreme depression of the thalamus)</li><li>Increase in the power of the frontal electrodes (Beta: is the result of sensory stimuli influencing the reticular activating system with desynchronization of thalamic pacemakers, maximal in the prefrontal regions)</li><li>Marked increase in hypercoherence/synchrony</li></ul>


</ul><i>
Note: Each anesthetic agent will have a different effect on the EEG. Their profile will change the closer they get to isoelectric. Increasing the dose of anesthetics will produce slowing, then burst suppression, then electro-cerebral silence (isoelectric EEG) <br><br>These maps are a patient who was in a car accident and was taking a combination of pain management medications. The blending of sedatives and hypnotics tends to produce an excessive slowing in the EEG.<br><br><img src="@@PLUGINFILE@@/hypnotics-sedatives.jpg" alt="" width="724" height="958" role="presentation" class="img-responsive atto_image_button_text-bottom"><br><br>Figure 10: Excessive slowing in the theta band as a result of combining hypnotics and sedatives.. Image generated from Neuroguide version 3.0.6.<br></i>